Seroquel dosage

4Adult data mean seroquel baseline score is based on patients included in the primary analysis; pediatric mean baseline score is based on all patients in the ITT population. 15 dry mouth (4. For preventing recurrence in bipolar disorder. These reports seroquel often occurred in the setting of tachycardia, dizziness, orthostatic hypotension and/or underlying cardiac/respiratory disease. 5.9 for seroquel placebo in adjunct therapy. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about.5, compared to seroquel a rate of about.6 in the placebo group. Based on clinical trial adverse event seroquel for sleep reports of blood creatine phosphokinase increase not dosage associated with neuroleptic malignant syndrome. QT Prolongation In clinical trials quetiapine dosage was not associated with a persistent increase in QT intervals. The extent to which the findings of increased mortality in observational studies may be attributed seroquel to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Patients dosage should be cautioned about performing any activity requiring mental alertness, such as operating a motor vehicle (including automobiles) or operating machinery, until they are reasonably certain quetiapine therapy does not affect them adversely. Based on a limited number (N8) of mother/infant pairs, calculated infant daily doses range from less than.01 mg/kg seroquel (at a maternal daily dose seroquel up to 100 dosage mg quetiapine).1 mg/kg (at a maternal daily dose seroquel of 400 mg). CYP3A4 inhibitors : Coadministration of ketoconazole, a potent inhibitor of cytochrome CYP3A4, resulted in significant increase in quetiapine exposure. In this study, there were seroquel no patients in the seroquel seroquel withdrawal dosage XR or placebo-treated groups with a baseline normal fasting glucose level ( 100 mg/dL) that dosage had an seroquel increase in blood glucose level 126 mg/dL. This, in turn, may inhibit reproductive function by seroquel impairing gonadal steroidogenesis in both female and seroquel male patients. There is no known treatment for established cases of tardive dyskinesia, although the syndrome may remit, partially or completely, if antipsychotic treatment is withdrawn. There may be new information. The effectiveness of seroquel as monotherapy for the maintenance treatment of bipolar disorder has dosage not been systematically evaluated in controlled clinical trials see Clinical Studies. Cerebrovascular Adverse Reactions, Including Stroke, In Elderly Patients With Dementia-Related Psychosis In placebo-controlled trials with risperidone, aripiprazole, and seroquel olanzapine in elderly subjects with dementia, there was a higher dosage incidence of cerebrovascular adverse reactions (cerebrovascular accidents and seroquel transient ischemic attacks) including fatalities compared to placebo-treated subjects. These include people who have (or have a family history of) depression, bipolar illness (also called manic -depressive illness or suicidal seroquel thoughts or actions. Human Data There are limited published data on the use of quetiapine for treatment of schizophrenia and other psychiatric seroquel xr disorders during pregnancy. Interference With Cognitive And Motor Performance Patients should be advised of the risk of somnolence or sedation (which may lead to falls especially during the period of initial dose titration. Key outcomes in these dosage trials were change from baseline in the Young Mania Rating Scale (ymrs) score at dosage 3 and 12 weeks for monotherapy and at seroquel 3 weeks for adjunct therapy. Inhibition of NET and partial agonist action at 5HT1A sites by norquetiapine may contribute to Seroquel's therapeutic efficacy as an antidepressant. 0.7 (1/138 respectively and for decreased total thyroxine was.8 (8/289). Re-initiation of Treatment in Patients Previously Discontinued Although there are no data to specifically address re-initiation of treatment, it is recommended that when restarting therapy of patients who have been off seroquel for more than one week, the initial dosing schedule should be followed. It is general clinical experience that the risk of suicide may increase in the early stages of recovery. There have been reports of false positive results in enzyme immunoassays for methadone and tricyclic antidepressants in patients who have taken quetiapine. Indications, indications, schizophrenia, seroquel is indicated for the treatment of schizophrenia. Children seroquel and Adolescents (ages 10-17) The efficacy of seroquel in the acute treatment of manic episodes associated with bipolar I disorder in children and adolescents (10 to 17 years of age) was demonstrated in a 3-week, double-blind, placebo-controlled, multicenter trial (study 4 in Table 20). Children And Adolescents In a placebo-controlled seroquel monotherapy study of adolescent seroquel patients (1317 years of age) with schizophrenia (6 weeks duration the mean change in fasting glucose levels dosage for seroquel (n138) compared to placebo (n67) was.75 mg/dL versus.70 mg/dL. A retrospective study of children and adolescents who received valproate, quetiapine, or both, found a higher seroquel incidence of leucopenia and neutropenia in the combination group seroquel versus the monotherapy groups. Hyperprolactinemia Adults: During clinical trials with quetiapine, the incidence of shifts in prolactin levels to a clinically significant value occurred.6 (158/4416) of patients treated with quetiapine compared.6 (51/1968) on placebo. The effect that symptomatic suppression has upon the long-term course of the syndrome is unknown. Patients should be observed for signs and symptoms of infection and neutrophil counts followed (until they exceed.5 x 109/L) (see section.1). The bioavailability of quetiapine is marginally affected by administration with food, with Cmax and AUC values increased by 25 and 15, respectively. The pharmacokinetics of quetiapine and norquetiapine are linear across the approved dosing range. In the open-label phase, patients were required to be stable on seroquel plus lithium or divalproex for at least 12 weeks in order to be randomized. The need for continuing existing EPS medication should be re-evaluated periodically. Several instruments were used for assessing psychiatric signs and symptoms in these studies, among them the Brief Psychiatric Rating Scale (bprs a multi-item inventory of general psychopathology traditionally used to evaluate the effects dosage of drug treatment in schizophrenia. Patients with an established diagnosis of diabetes mellitus who are started on atypical antipsychotics should be monitored regularly for worsening of glucose control. Treatment with Seroquel was initiated at 50 mg/day and on day 2 increased to 100 mg/day; subsequently the dose was titrated to a target dose (mania 400-600 mg/day; schizophrenia 400-800 mg/day) using increments of 100 mg/day given two or three times daily. For patients who were randomized to placebo, the mean weight gain during the open label period was.39 kg, and by week 48 of the randomized period the mean weight gain was.89 kg, compared to open label baseline. Bipolar Depression Safety and effectiveness of seroquel in pediatric patients less than 18 years of age with bipolar depression dosage have not been established. Increased mortality IN elderly patients with dementia-related psychosis; and suicidal thoughts AND behaviors. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms. Caution should be exercised if quetiapine is prescribed to elderly patients with. In vitro studies using human liver microsomes revealed that the cytochrome P450 3A4 isoenzyme is involved in the metabolism of quetiapine to its major, but inactive, sulfoxide metabolite and in the metabolism of its active metabolite N-desalkyl quetiapine. These hepatic enzyme elevations usually occurred within the first 3 weeks of drug treatment and promptly returned to pre-study levels with ongoing treatment with seroquel. There were also very rare reports of overdose of seroquel alone resulting in death or coma. Doses were 10 to 250 mg/kg in rats and 75 to 750 mg/kg in mice; these doses are.1-3, and.1-4.5 times the maximum recommended human dose (mrhd) of 800 mg/day on mg/m body surface area, respectively. Adverse reactions reported since dosage market introduction which were temporally related to quetiapine therapy include anaphylactic reaction, cardiomyopathy, drug reaction with eosinophilia and systemic symptoms (dress hyponatremia, myocarditis, nocturnal enuresis, pancreatitis, retrograde amnesia, rhabdomyolysis, syndrome of inappropriate antidiuretic hormone secretion (siadh Stevens-Johnson. The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric. In acute bipolar mania trials in adults, the proportions of patients with transaminase elevations of 3 times the upper limits of the normal reference range in a pool of 3- to 12-week placebo-controlled trials were approximately 1 for both seroquel (3/560) and placebo (3/294). In some patients, a worsening of more than one of the metabolic parameters of weight, blood glucose, and lipids was observed in clinical studies. 400 mg Tablets ( NDC ) yellow, capsule-shaped, biconvex, film coated tablets, seroquel intagliated with 'seroquel' on one side and '400' on the other side, are supplied in bottles of 100 tablets, and hospital unit dose packages of 100 tablets. Distribution Quetiapine is widely distributed throughout the body with an apparent volume of distribution of 104 L/kg. Seroquel is not approved for the treatment of patients with dementia-related psychosis see also boxed warning and Increased Mortality In Elderly Patients With Dementia-Related Psychosis. Body Temperature Regulation Although not reported with seroquel, disruption of the body's ability to reduce core body temperature has been attributed to antipsychotic agents. The patients in these trials died from a variety of causes that were consistent with expectations for this population. Older adults dosage may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, lightheadedness, and QT prolongation (see above). When the CYP3A4 inhibitor is discontinued, the dose of seroquel should be increased by 6 fold see clinical pharmacology and drug interactions. Tell the healthcare provider about all the medicines that you take or recently have taken including prescription medicines, over-the-counter seroquel medicines, herbal supplements and vitamins. 6.6 Special precautions for disposal and other handling No special requirements. In all cases, let your doctor know if you are or may become pregnant or if you are breastfeeding before taking Seroquel). The primary efficacy results of these studies in the treatment of mania in adults is presented in Table. In short-term placebo-controlled monotherapy trials, the incidence of reciprocal, shifts in T3 and TSH dosage was.0 for both quetiapine (1/4800) and placebo (0/2190) and for T4 and TSH the shifts were.1 (7/6154) for quetiapine versus.0 (1/3007) for placebo. At steady-state, the dose-normalised plasma levels of the parent compound, quetiapine, in children and adolescents (10-17 years of age) were in general similar to adults, though Cmax in children was at the higher end of the range observed in adults. Seroquel data in combination with divalproex or lithium in acute moderate to severe manic episodes at 3 and 6 weeks is limited; however, combination therapy was well tolerated. If you've been prescribed immediate-release quetiapine tablets for schizophrenia or a manic episode, these are usually taken twice a day. It is important that the lowest effective dose is used for maintenance therapy. Different dosing schedules exist for each seroquel indication. Physostigmine may be used if there are no ECG aberrations. In placebo-controlled clinical trials with children and adolescent patients, quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for schizophrenia, bipolar mania and bipolar depression (see section.8). This database includes 677 patients exposed to seroquel for the treatment of schizophrenia and 393 children and adolescents (10-17 years old) exposed to seroquel for the treatment of acute bipolar mania. It is unknown whether the suicidality risk extends to longer-term use,.e., beyond several months. Talk with the doctor about the risks and benefits. The reduction in total and free thyroxine (T4) of approximately 20 at the higher end of the therapeutic dose range was maximal in the first six weeks of treatment and maintained without adaptation or progression during more chronic therapy. The following table summarises ADRs that occur in a higher frequency category in children and adolescent patients (10-17 years of age) than in the adult population or ADRs that have not been identified in the adult population. The identity of the pigment could not be determined, but was found to be co-localized with quetiapine in thyroid gland follicular epithelial cells. Somnolence may lead to falls. Quetiapine at doses of 750 mg/day did not affect the single seroquel dose pharmacokinetics of antipyrine, lithium or lorazepam (Table 18) see drug interactions. The safety results showed a higher incidence of extrapyramidal symptoms reported.8 of patients in the lithium add-on group and.6 in the placebo add-on group, the majority of which consisted of tremor, reported.6. This medication may make you sweat less, making you more likely to get heat stroke. Seroquel is a prescription medicine dosage used to treat: schizophrenia in people 13 years of age or older bipolar disorder in adults, including: depressive episodes associated with bipolar disorder manic episodes associated with bipolar I disorder alone or with lithium. Metabolism And Elimination Following a single oral dose of 14C-quetiapine, less than 1 of the administered dose was excreted as unchanged drug, indicating that quetiapine is highly metabolized. Quetiapine was administered in the diet to mice at doses of 20, 75, 250, and 750 mg/kg and to rats by gavage at doses of 25, 75, and 250 mg/kg for two years. Seroquel can cause serious side effects, including: See What is the most important information seroquel I should know about seroquel? Mean increases in heart rate were.8 bpm and.4 bpm for seroquel 400 mg and 600 mg groups, respectively, compared to a decrease.7 bpm in the placebo group see warnings AND precautions. Quetiapine should be used with caution in patients with known cardiovascular disease, cerebrovascular disease, or other conditions predisposing to hypotension.

Seroquel high

Retrieved seroquel from Adler,. Australian New Zealand Journal of Psychiatry, 0 (0 high 20122014. Street names for seroquel high quetiapine high include quell, snoozeberries, and, susie-Q. GPs prescribed.5x high more quetiapine than seroquel specialists in high 2011, whereas specialists prescribed 4x more than GPs in 2002. Maximum dosage: 800 mg once per day. 15 dry mouth (4. Legal Status (as of November seroquel 2017) United States Prescription-only Other countries Its also prescription-only in Australia, Canada, and the. However, at least 2 days should pass between the additional dosage adjustments. Cortical effects of quetiapine in first-episode schizophrenia: A preliminary functional magnetic high resonance imaging study. Neurometabolite Effects of Response to Quetiapine and Placebo in Adolescents with high Bipolar Depression. Keep high this drug away from light. Chemistry Pharmacology Chemistry Quetiapine is a dibenzothiazepine derivative with structural similarities to clozapine. Days 2 and 3: Your doctor will increase your dose by 2550. Biological Psychiatry, 56 (12 938942. Australian and New Zealand Journal of Psychiatry. Data has high been reported to indicate that the majority of patients responded between 400 mg per day to 800 mg per day.

Side effects of seroquel

"This is one of the ironies with this massive increase in the prescription rate in Australia - when you stack it up against other medications and other treatments, it doesn't really stand out as a particularly good drug." Patients. High cholesterol - up to 17 percent, fatigue - up to 11 percent. "We see quetiapine being used side in anxiety, it's used in depression, it's being used for insomnia, it's used a lot in people who have drug and alcohol problems, it's used in things like anorexia nervosa he seroquel said. Schneider LS, Dagerman KS, Insel P "Risk seroquel of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials." jama 294 (2005. This can lead to unwanted effects and problems managing your illness. Quetiapine is not seroquel approved by the FDA for use in the treatment of behavioral disorders in elderly patients seroquel with dementia. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Center for Drug Evaluation and Research "FDA Public Health Advisory. Although not seroquel all of these side effects may occur, if they do occur they may need medical attention. Was the only adverse reaction leading to discontinuation that occurred at an incidence of 2 in seroquel XR in MDD trials. Thanks for your feedback! Call your doctor if you have fever, stiff side muscles effects and confusion effects one commercial said. "It's where your heart starts beating extremely fast and out of control. In Tables 22 and 23, dystonic events included nuchal rigidity, hypertonia, dystonia, and muscle rigidity; parkinsonism included cogwheel rigidity and tremor; akathisia included akathisia only; dyskinetic event included tardive dyskinesia, dyskinesia and choreoathetosis; side and other extrapyramidal event included restlessness and extrapyramidal disorder. Decreased Hemoglobin Adults: In short-term placebo-controlled trials, decreases in hemoglobin to 13 g/dL males, 12 g/dL females on at least one occasion occurred.3 (594/7155) of quetiapine-treated patients compared.2 (219/3536) of patients treated with placebo. Among children and adolescents, a weight gain of 7 or greater occurred in 7 to 21 of patients receiving this drug compared with up to 7 in placebo patients. Constipation, dizzy, drowsiness, dry Mouth, feeling Weak, head Pain. Bipolar I Disorder, Manic or Mixed Episodes: There were no effects adverse reactions leading to discontinuation that occurred at an incidence of 2 for seroquel XR in the bipolar mania trial. Table 12: Adverse Reactions in 6-Week Placebo-Controlled Clinical Trials for the Treatment of Schizophrenia Preferred Term seroquel XR (N951) Placebo (N319) Somnolence 1 25 10 Dry Mouth 12 1 Dizziness 10 4 Extrapyramidal Symptoms 2 8 5 Orthostatic. Extrapyramidal Symptoms (EPS) Dystonia Class Effect : Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible individuals during the first few days of treatment. Among patients with major depressive disorder receiving the extended-release formulation of this drug, a FBG greater than 126 mg/dL occurred in 7, 12, and 6 of those receiving 150 mg, 300 mg, or placebo. Irritated or runny side nose, vision problems.


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  1. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Talk to your doctor if you are using marijuana (cannabis). Dyslipidemia : Undesirable alterations in lipids have been seroquel dosage observed with seroquel XR use.

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  3. Amlodipine, Diltiazem: See Warnings and Precautions what is seroquel used for (5.4) Nifedipine: Nifedipine is a substrate what is seroquel used for for CYP3A.

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Seroquel dosage

EpicureanPiranha | April 3rd, 2011 - 16:00

Challah is one of my favourite egg breads ~ the aroma of the loaves baking is sublime, and the rich dough is incredibly tender whith just a hint of sweetness! With cold butter, and perhaps some wild berry preserves, I could easily eat a whole loaf when it’s still warm from the oven (I actually did this a few years ago!).  But I’d never tried baking one until last year. After researching recipes for this delicious Jewish specialty in my cookbooks and on the web, I had chosen the recipe I’d found in the Fleischmann’s Yeast “Best Ever Breads”cookbook (using Fleischmann’s traditional active dry yeast). The proportion of butter and eggs seemed the most promising for what I wanted to achieve.

My first Challah - Fleischmann Yeast recipe - IV 04F

My first Challah, prepared using the Fleischmann’s Yeast recipe.

I have to admit that I was very pleased with the results. The baked loaves looked gorgeous, and had a wonderful flavour and texture. But the bread just wasn’t as rich tasting ~ and the dough not as golden ~ as I’d hoped! So I went back to my research, but still could not find a recipe that seemed better. Since I couldn’t find what I was looking for, I decided I’d have to create my own recipe!

Epi's Own Challah Recipe 06

Rich, golden loaves of challah, prepared from my own recipe.

The result was, to say the least, fabulous! But this assessment is not only my own! Several friends and family members, including my sister, who are excellent bakers and foodies, all agreed. My parents are probably the most critical bread eaters I know, and for good cause! One of my aunts on my mother’s side and my grandmother on my father’s side made the most exquisite breads! I’ve had bread that tasted as good as my aunt’s, but never tasted better, even in Europe where I lived for 21 years! And my parent’s verdict was also that my recipe for challah produced the best egg bread they had ever tasted.

Epi's Own Challah Recipe - sliced

Slices of my rich, golden egg bread, still warm from the oven, with a jar of my home-made golden-amber caramel ~ ambrosia!

The bread cooks to a gorgeous golden brown, and the dough is wonderfully tender, and has the colour of pale yellow beaten eggs. The aroma while it’s baking and once it’s out of the oven is quite simply impossible to resist! Perfection! I had several pieces of it while it was warm, with cold butter and some of my golden amber home-made caramel ~ sheer delight!

After having tasted literally dozens upon dozens of challahs in Montreal, England, and New York, only one baker I knew of made a richer tasting loaf that was as lovely in texture ~ and I’ve tasted hundreds of different Challah!!! He is based in London, in Mill Hill East, where I lived for several years. But now, to my delight, I can say I have created a challah recipe that beats his hands down ! I do hope you will give it a try and let me know what you think ♥

Oh, and I must also tell you that the second time I baked some of this bread, I had an extra yolk, so I added that as well (i.e. for a total of 4 large eggs and 5 large egg yolks). Oh my! It was almost like brioche, but I liked this more ♥

What is seroquel used for

Quantity Ingredient  
20 ml Granulated sugar
250 ml Warm water (38C)
30 ml Active dry yeast
150ml Liquid manuka or other honey
4 large Eggs, room temperature
4 large Egg yolks, room temperature Lightly beat eggs with yolks.
150 g Butter, melted  
10 ml Salt
1,750 l All-purpose flour
350 ml Golden raisins (optional)
1 Large egg yolk, lightly beaten
30 ml Poppy seeds or sesame seeds

Seroquel dosage

NB: I used a powerful KitchenAid® mixer to make this dough, but any heavy duty mixer can be used, or prepare it according to the traditional method for making bread which I describe in detail in my How-to section on making great bread.

  • Warm the large bowl of your stand mixer with hot water. Empty this then dissolve the sugar in the warm water specified in my recipe above. Sprinkle in the yeast; let stand until frothy, about 10 minutes.
  • Add honey and the beaten eggs and yolks to dissolved yeast. Beat with paddle attachment for 10 seconds on speed 2.
  • Add melted butter and salt, and beat on speed 2 for 10 seconds.

NB: For the following steps always start at the “stir” setting and never use a setting higher than 2.

  • Add 500 ml flour to yeast mixture and beat 15 seconds or until well blended, using paddle attachment. Scrape down the bowl once.
  • Add another 500 ml flour and beat 15 seconds or until well blended, using paddle attachment. Scrape down bowl once.
  • Switch to dough hook, cleaning paddle well and add any bits of dough to mixture in bowl.
  • Add another 500 ml flour and knead 30 seconds or until well blended, using dough hook. Scrape down bowl once.
  • Add the last 250 ml flour and knead 15 to 30 seconds or until well blended, using dough hook. Scrape down bowl once or twice. Knead another 30 seconds.
  • Touch dough. If it feels sticky, add about 30 ml flour and knead in well, about 60 seconds. If dough is really sticky, add another 30 ml and knead, but make sure dough is not too dry!
  • Knead for another 5 minutes or until dough is smooth and elastic. NB: A more moist dough is tougher to handle but once baked will yield a more delicate texture.
  • Gather into a ball and place in a clean, lightly greased bowl (I use butter), turning dough so that it is completely covered. Cover the bowl loosely with cling film and place in a draft free area; allow to rest for 50 – 60 minutes, or until doubled in size.
  • Once the dough has doubled in size and an indentation remains when dough is poked with 2 fingers (then it’s ready!), punch it down lightly and turn out on a floured surface. Knead lightly just a few times, kneading in raisins at this time if you wish (don’t knead more than 3 or 4 times). Let dough rest for 5 minutes or so.
  • Line a large baking sheet with a wide sheet of baking parchment, or grease the sheet lightly.
My first Challah - Fleischmann Yeast recipe - I 02

Shaping the partially raised dough into attractive braided loaves.

The following technique for making beautiful, double braided loaves is from the Fleischmann’s Yeast cookbook, but you can shape the dough into any shapes you prefer, including individual loaves.

  • Divide the dough into two. Gather half of the dough into a ball and place it back in the bowl, leaving it covered.
  • Meanwhile, take the other half and divide into two parts, one equal to 1/3 and the other 2/3 of the dough. Take the larger part, cut into three equal pieces, and roll each into a long 30.5 cm (12 inch) strand. Braid, pinch ends to seal, and place on baking sheet. Now do the same with the smaller piece of dough, rolling each 1/3 into 25.4 cm (10 inch strands). Braid, pinch the ends to seal, and place on top of larger braid.
  • Repeat with remaining dough.

Alternatively, make a single 4-strand braid like so:

  • Divide dough into quarters; roll each into 18-inch 45 cm long ropes. Place side by side on greased rimmed baking sheet; pinch together at one end. Starting at pinched end, move second rope from left over rope on its right. Move far right rope over two ropes on left. Move far left rope over 2 ropes on right. Repeat until braid is complete; tuck ends under braid.
  • Cover with cling film or a clean tea towel and allow to rise for 40 to 60 min until doubled in size.

Seroquel dosage

  • Once the loaves have risen, preheat the oven to 180C (350F), and place rack in bottom third of oven.
  • Glaze the challahs with the beaten egg and water, and sprinkle with poppy seeds if desired.
  • Bake for about 25 – 30 minutes (or 35 to 45 minutes for large braid) until golden and they sound hollow when tapped on the bottom. Don’t underbake!

Seroquel high

  1. Plexguard says:

    Can someone please tell me how much flour I should put in the challah? Because it says to put 1,750 l All-purpose flour When I try to convert that it says 13oz which makes no sense.

    • Hi Yeshai

      1,750 l in metric equals one litre and 750 millilitres (ml). If you decide to use the “cup” measurement, then 1,750 l = 7 cups

      250 ml = a little more than one cup (ie: where 1 cup = 8 fluid ounces)

      In the metric system, the lower case letter “l” and occasionally the upper case “L” are the abbreviations for litre, and:

      one litre = 1000 ml
      = 250 ml x 4

      In baking, particularly when making bread, it’s the proportion of ingredients that matters. In other words, it doesn’t really matter what measure you use for ingredients, as long as the proportion of each ingredient to the others is maintained. So, for example, if you decide to use an 8 fluid ounce cup as your base measure, then you should not mix this with metric cups which are in ml.

      It’s more difficult to convert litres (or millilitres) to grams or ounces (ie: weight as opposed to fluid), because to get the correct conversion you have to be able to specify what you are weighing. For example, when measuring the same volumes of each, butter will weigh more than all-purpose flour. Different types of flour will also have different weights per volume! I used ml in my recipe because I learned how to make bread from my aunt using my grandmother’s bread recipe, and measurements were in cups way back then. So I’ve always used metric cups to measure amounts of flour when I bake breads :-)

      There are many conversion resources available on the web if ever you are wondering what a measurement in a recipe represents. You can try this one which lets you enter the measurement you want to convert, what to convert it to, as well as the ingredient: Online Conversion – Weight to Volume.

      Hope this helps and do let me know how your bread turns out!

      ~ marie, the EpicureanPiranha

  2. trevifreeze says:

    I made your recipe today exactly exactly as you had written it out and it turned out absolutely beautiful!! I am an avid bread maker and this was truly a successful recipe. Thank you thank you for this amazing and well thought out recipe (and instruction).

    • Thank you so much :-) I’m so pleased to know you like the bread and that my instructions were easy to follow! It’s always difficult for someone (like me) who knows how to bake/cook a specific recipe, to write out instructions that are useful to people who want to try making it; I don’t want to bore good cooks, but at the same time, I want to provide enough info for the novice cook to get it right…which is why I’m so pleased. And I’m especially thankful that you took the time to write me a message ~ I always look forward to feedback, because that’s how I can improve what I do so that it’s more helpful to my readers and members. So thank You, my dear!

      Have a delicious day!

      ~ marie, the EpicureanPiranha

  3. Alexandra says:

    I’m a german expat in the US. I’m confused: why are you using ml where it should be gr? One is liquid, the other volume.

    Perhaps it’s not important, but I’m befuddled.

    • Hi Alexandra

      Thank you for registering on my blog and for asking this question, which always raises lots of debate!

      The main reason is that in North America, many home bakers do not own scales (although this is changing, I hope!), but measuring cups are always graduated in both fluid ounces and milliliters. Also, it’s important to note that different types of flour will have different weights per volume. So, for example, whole-wheat flour has a greater weight per volume than all-purpose flour.

      Another reason is that I was used to making bread using 8 fluid oz cups, from many years ago! Nowadays, even though I use metric for almost everything, and all my measuring cups are metric only, I still use cups (a 250 ml cup!) to measure flour for my bread baking!

      But if you would like to convert dry measures from ml to g, then this is a good source if you live in the USA (click on the link): What’s Cooking America. And there are many other conversion guides on the net for converting baking ingredients.

      I hope this helps answer your question! And thanks again for registering. Oh, and do let me know what you think of my recipe if you bake it!

      Have a delicious day!

      ~ marie, the EpicureanPiranha

  4. Karen says:

    The description of your quest convinced me to try your Challah recipe. Even with my approximate conversions, it was phenomenal!! My search for the best challah recipe has indeed come to an end. Thank-you!

    • Hi Karen

      Just read your delightful message on my Challah recipe and I’m so happy you gave it a try and loved it!

      I’ve been very busy (with renovating & redecorating our home!), and haven’t updated my webzine in a while I’m afraid, but do have a look at next week; I’ll be posting several new articles and recipes you may like!

      If there are any recipes, food, or baking/cooking-related questions you’d like answered, let me know! Take care and thank you so much for being an active member of!

      Have a delicious day,


  5. Rosie says:

    When are you going to make us more of this fantastic bread, Marie? It’s so good, and dad loves it! Your photo is so beautiful!!!


    Mom xxx

  6. cakebooks says:

    Would dearly love to make this recipe tomorrow or Saturday, is there any way the measurements could be converted to American kitchens? I tried to look it up online but I don’t think that flour is measured by liters? I am confused but drooling over this bread, please advise?

    • Hello Amie

      I’m so sorry I missed your question and didn’t see it until today! On Friday, I was busy planning & shopping for a dinner party on Easter Sunday, and Saturday I had two unexpected guests (my sweetheart’s 2 teenaged sons each invited friends over for the day!) so ended up cooking much more than I thought on Saturday & Sunday, in addition to all the preparation!

      Before I reply more fully, thank you so much for registering and for your comment and support

      I prefer to use metric measurements for two main reasons:
      (1) weighing ingredients in grams is so much more accurate than trying to measure them by volume, and
      (2) the metric system is based on the decimal system (divisible by 10) and is so simple!

      But to answer your question:
      A simple conversion isn’t always possible, because the Imperial, US, and Australian measurement systems are all different even though they sometimes use the same terms! For example, take a cup of plain (all-purpose) flour. The cup measurement is different depending on whether it’s a Canadian, US, or Imperial cup! Which do you use? Also, an 8 fl oz cup of flour, depending on the type of flour and the humidity, will have different weights! This difference can be enough to ruin your cake or pastry.

      Whenever I mention a cup measurement in my recipes, it’s either because it’s an old recipe I’ve had handed down to me, or one that I found in a cookbook or on the web. This will be an 8 fl oz cup = 250 ml = Canadian, Australian, New Zealand, South African and Lebanon cup measure.

      I also use a 250 ml cup measurement for flour when making bread, simply because I learned to make bread the traditional way, with my aunt, using my grandmother’s method and recipes. My grandparents lived in the countryside, and baked in wood burning stoves back then! They didn’t even use graduated measuring cups when baking bread. I remember my grandmothers and aunties having huge tin containers of flour in their pantries, and there would be an old tea cup in the tin for scooping out small amounts. But they didn’t even use this to make bread ~ they’d just pour the flour into a huge metal bowl, then add salt and water, all by eye! Bread was made by “feel” in those days. And one of my aunts eventually figured out the measurements in cup measures. I also had very old books on baking bread, and they all used fluid ounzes as the measurement for flour. Since I like to use metric, I simply started using a 250 ml cup … so no logical explanation I’m afraid!

      That being said, you only need very precise measurements when baking cakes, cookies, fancy pastries, or when preparing candies, cooked icings, and desserts and so on. Most savoury dishes don’t require the same level of precision. Even for most cakes and desserts, I personally always use my metric measurement cups if an 8 oz cup measurement is specified ~ what’s essential in baking is proportion!

      Here’s a very short guide of approximate measures, and below this I’ve provided links to two different conversion guides, and to a conversion calculator, that you can use:

      Metric and equivalent Canadian/Australian Measures
      1 ml ~ 1/4 tsp
      2.5 ml ~ 1/2 tsp
      5 ml ~ 1 tsp
      60 ml ~ 1/4 cup
      80 ml ~ 1/3 cup
      125 ml ~ 1/2 cup
      250 ml ~ 1 cup

      There are loads of conversion guides available on the web, but some are confusing, and some are incorrect. Here are a few which are useful:

      1. The UK BBC Good Food Guide’s conversion: calculator
      2. What’s Cooking America cooking conversion guide: (for US measures)
      3. Creative Cake Decorating conversion guide: for making cakes

      I hope this helps! Please let me know if you still have any questions.

      ~ marie, the EpicureanPiranha

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